Is Lopid a statin?
Lopid and Lipitor belong to different drug classes, Lopid is a lipid-regulating agent and Lipitor is an HMG-CoA reductase inhibitor (a "statin" drug). Side effects of Lopid and Lipitor that are similar include nausea, diarrhea, headache, and muscle pain.
What drug class is gemfibrozil in?
Gemfibrozil is in a class of lipid-regulating medications called fibrates. It works by reducing the production of triglycerides in the liver.
What is Lopid drug class?
Gemfibrozil (Lopid) is a fibrate, which is a class of medications that help with cholesterol problems, especially high triglycerides. Statins also help with cholesterol problems but work differently than gemfibrozil (Lopid).
Fibrate drugs, such as gemfibrozil (Lopid) and fenofibrate (TriCor), are undoubtedly the best tools to address the condition characterized by high triglycerides, low high-density lipoprotein (HDL), and small dense low-density lipoprotein (LDL) (atherogenic dyslipidemia), but the most recent guidelines from both the
Conditions treated by Vascepa and Lovaza
|Used along with a high-dose statin to reduce cardiovascular complications in adults with triglycerides ≥ 150 mg/dL||Yes||No|
|Used along with diet to lower triglyceride levels in adults with severe hypertriglyceridemia (≥500 mg/dL)||Yes||Yes|
GENERIC NAME: GEMFIBROZIL - ORAL (jem-FYE-broh-zill)
Lotensin is a prescription medicine used to treat the symptoms of High Blood Pressure (Hypertension). Lotensin may be used alone or with other medications. Lotensin belongs to a class of drugs called ACE Inhibitors.
Lowering LDL cholesterol may reduce the risk of hardened arteries, which can lead to heart attacks, stroke, and circulation problems. Colestid is available in generic form.
Lovastatin is used together with diet, weight-loss, and exercise to reduce the risk of heart attack and stroke and to decrease the chance that heart surgery will be needed in people who have heart disease or who are at risk of developing heart disease.
Gemfibrozil is used along with a proper diet to help lower fats (triglycerides) and raise "good" cholesterol (HDL) in the blood. It may also help to lower "bad" cholesterol (LDL). Gemfibrozil belongs to a group of drugs known as "fibrates." It works by decreasing the amount of fat produced by the liver.
Conclusions: Compared with gemfibrozil, fenofibrate produced significantly greater reductions in total cholesterol, LDL, and triglycerides and significantly greater increases in HDL. These changes were evident in patients receiving and not receiving concomitant statin therapy.
List of Fibric acid derivatives:
|Drug Name||Avg. Rating||Reviews|
|Trilipix (Pro) Generic name: fenofibric acid||5.0||18 reviews|
|TriCor (Pro) Generic name: fenofibrate||5.9||15 reviews|
|Lopid (Pro) Generic name: gemfibrozil||6.5||6 reviews|
|Lipofen (Pro) Generic name: fenofibrate||7.3||2 reviews|
What are bile acid sequestrants? Bile acid sequestrants such as cholestyramine (Questran, Prevalite), colestipol (Colestid, Flavored Colestid ), and colesevelam (Welchol) are medications for lowering LDL cholesterol in conjunction with diet modification.
Gemfibrozil is available as the brand-name drug Lopid. It's also available as a generic drug. Generic drugs usually cost less than the brand-name version.
Zetia and the fibrate drug class
Fenofibrate belongs to the fibrate drug class. Zetia is FDA-approved to treat mixed high cholesterol when used with fenofibrate.
Examples of fibrates include: clofibrate (Atromid-S) gemfibrozil (Lopid) fenofibrate (Antara, Lofibra, and Triglide)
Fibrates have a significantly greater effect in reducing plasma Lp(a) concentrations than statins. Addition of fibrates to statins can enhance the Lp(a)-lowering effect of statins.
2 The name change is intended to minimize the potential for such errors in the future. Packaging bearing the name LOVAZA will be available in pharmacies later this summer. Indications and usage OMACOR is indicated as an adjunct to diet to reduce very high (≥500 mg/dL) triglyceride (TG) levels in adult patients.
Lovaza and Omtryg contain omega-3-acid ethyl esters (principally EPA and DHA: 0.465 g EPA and 0.375 g DHA in each 1-g capsule for Lovaza and 1.2-g capsule for Omtryg), whereas Epanova is a mixture of polyunsaturated free fatty acids, also referred to as carboxylic acids, the most abundant of which are EPA and DHA (
The results showed that DHA had a stronger anti-inflammatory effect than EPA: DHA lowered the genetic expression of four types of pro-inflammatory proteins, whereas EPA lowered only one type. DHA lowered white blood cell secretion of three types of pro-inflammatory proteins, whereas EPA lowered only one type.
Serum concentrations of lipoproteins should be monitored regularly and dosage adjusted to individual requirements. In clinical trials, doses have ranged from 900—1600 mg/day PO. Gemfibrozil should be discontinued if serum lipoprotein concentrations do not improve substantially after 3 months of therapy.
Losartan (Cozaar) is available as a generic medication and may be significantly cheaper compared to the brand version.
Meloxicam is used to treat arthritis. It reduces pain, swelling, and stiffness of the joints. Meloxicam is known as a nonsteroidal anti-inflammatory drug (NSAID).
Angiotensin-converting enzyme inhibitor (ACE inhibitors) drugs include Benazepril (Lotensin), Captopril (Capoten), Enalapril/Enalaprilat (Vasotec oral and injectable), Fosinopril (Monopril), Lisinopril (Zestril and Prinivil), Moexipril (Univasc), Perindopril (Aceon), Quinapril (Accupril), Ramipril (Altace), and
Questran and Colestid are certainly reasonably safe with a few precautions. They must be taken at the right time because they also can bind other things like medications a patient is taking. So they are reasonable treatments, but again have not been proven to be effective in patients with irritable bowel syndrome.
What drug tier is colestipol typically on? Medicare prescription drug plans typically list colestipol on Tier 2 of their formulary. Generally, the higher the tier, the more you have to pay for the medication.
Hepatotoxicity. There is little evidence that colestipol causes liver injury. Mild elevations in serum aminotransferase and alkaline phosphatase levels have been reported in small numbers of patients on bile acid resins, although the elevations have been mild, transient and without accompanying symptoms.
Lovastatin and simvastatin are chemically similar. The central difference between these two statins is that simvastatin tends to be more effective at lowering the targeted bloodstream cholesterol levels.
Conclusion: Rosuvastatin dominates atorvastatin, pravastatin, and simvastatin because it is more effective and less costly, and it may be considered cost-effective compared with generic lovastatin. The most cost-effective two-statin formulary contained lovastatin and rosuvastatin.
Examples of drugs that can cause interactions with lovastatin are listed below.
Fenofibrate oral tablet is available as brand-name drugs and as a generic drug. Brand names: Fenoglide, Tricor, and Triglide. Fenofibrate comes in two forms: oral tablet and oral capsule. Fenofibrate oral tablet is used to treat high cholesterol levels.
Fenofibrate is in a class of medications called antilipemic agents. It works by speeding the natural processes that remove cholesterol from the body.
In other areas, though, fibrates actually have the edge. They are substantially better at boosting HDL levels, and only two statins, atorvastatin (Lipitor) and rosuvastatin (Crestor), can match their ability to reduce triglyceride levels. Gemfibrozil (Lopid) and fenofibrate (TriCor) appear equally safe and effective.